Evidence for distinctive mechanisms of S-nitrosoglutathione metabolism by AdhC in two closely related species, Neisseria gonorrhoeae and Neisseria meningitidis.

نویسندگان

  • Adam J Potter
  • Stephen P Kidd
  • Michael P Jennings
  • Alastair G McEwan
چکیده

The adhC gene from 11 strains of Neisseria gonorrhoeae was distinguished from its homologue in Neisseria meningitidis by the presence of a premature stop codon caused by a single base insertion. Mutational analysis showed that NADH S-nitrosoglutathione oxidoreductase activity was associated with adhC in Neisseria meningitidis but not in Neisseria gonorrhoeae.

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عنوان ژورنال:
  • Infection and immunity

دوره 75 3  شماره 

صفحات  -

تاریخ انتشار 2007